1 edition of Nitrates in coronary heart disease found in the catalog.
Nitrates in coronary heart disease
by Published for Medisinsk fysiologisk forenings forlag, Oslo by Blackwell Scientific Publications in Oxford, Boston, Mass
Written in English
|Statement||editor, John K. Kjekshus.|
|Series||The Scandinavian journal of clinical & laboratory investigation -- v. 44, suppl. 173 (1984), Scandinavian journal of clinical & laboratory investigation -- 173.|
|Contributions||Kjekshus, John., Norsk cardiologisk selskap.|
|The Physical Object|
|Pagination||91 p. :|
|Number of Pages||91|
Search within book. Front Matter. Pages I-VIII. PDF. Pharmacology. Front Matter. Lack of Tolerance Development to the Hemodynamic Effects of Nitrates in Patients with Chronic Congestive Heart Failure. Joseph A. Franciosa. Pages Coronary Heart Disease. Front Matter. Pages PDF. Additional efficacy stems from the ability of the nitrates to replenish the deficient endothelium-derived relaxing factor (EDRF), nitric oxide (NO), in patients with coronary heart disease and also to inhibit platelet aggregation. In stable angina pectoris, the antianginal and anti- ischemic effects of oral nitrates are well established.
Nitrates are medications that relieve chest pain (angina) by dilating the blood vessel allowing more blood to flow. In patients with narrowed arteries of the heart nitrates can dilate the vessel allowing more blood flow and reducing symptoms of angina (chest pain).. Patients who have had previous heart attacks or angina may be prescribed nitrates. ISBN: OCLC Number: Description: x, pages: illustrations ; 25 cm: Contents: Pathophysiology of myocardial ischemia: major clinical syndromes / Udho Thadani, Edwin G. Olson and Stephen F. Hamilton --Approach to therapy of ischemic heart disease / Lyle J. Swenson --Mechanism of actions of nitrates / Jonathan Abrams --Mechanism of actions of beta .
The purpose of this study was to assess the effects of nitrates on changes in the R wave after exercise in a group of patients with coronary heart disease. MATERIALS AND METHODS. The population under study comprised 44 patients with coronary heart disease (39 men and five women). Nitrates act via nitric oxide signalling pathways and exert endothelium-independent vasodilatation, leading to an increase in coronary perfusion and reductions in cardiac pre- and post-load. 1, 2 With these pharmacological features, nitrates acutely improve cardiac conditions, such as angina attacks and acute heart failure.
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The influence of chronic use of nitrates in patients with coronary heart disease has not been analysed for prognosis. We were able to study mortality rates in patients who initially were randomized for nitroglycerin treatment or control 1½ year following the acute event. 3/28 patients died compared to 7/23 in the control : W.-D.
Bussmann. Print book: Conference publication: EnglishView all editions and formats: Rating: (not yet rated) 0 with reviews - Be the first.
Subjects: Coronary heart disease -- Treatment -- Congresses. Nitrates -- Therapeutic use -- Congresses. Coronary heart disease -- Treatment. View all subjects; More like this: Similar Items. If you have angina-- chest pain that happens when the arteries to your heart are blocked or narrowed -- your doctor may prescribe medicines called nitrates.
They relax your arteries so blood can. The role of nitrates in coronary heart disease. Abrams J(1). Author information: (1)Department of Cardiology, University of New Mexico School of Medicine, Albuquerque.
The organic nitrates are a safe and effective choice for the management of ischemic syndromes related to coronary heart by: The effects of sublingual nitroglycerin on myocardial blood flow in patients with coronary artery disease or myocardial hypertrophy.
Am Heart J. May; 77 (5)– MARCHETTI GV, MERLO L, ANTOGNETTI RM. THE EFFECTS OF NITROGLYCERIN ON THE CORONARY BLOOD FLOW AND OXYGEN CONSUMPTION OF THE MYOCARDIUM IN ANESTHETIZED DOGS. Am J by: Calcium channel blockers, nitrates, and ranolazine are used as adjunctive or second-line therapy when beta blockers are ineffective or contraindicated.
Select patients may benefit from coronary. Organic nitrates are drugs that widen arteries by increasing their supply of nitric oxide; that's how they open the partially blocked coronary arteries in patients with angina. Coronary Heart Disease: Selected full-text books and articles Almost Half of US Adults Have Some Form of Heart Disease By Krisberg, Kim The Nation's Health, Vol.
49, No. 2, April Nitrates are vasodilators (dilators of blood vessels that increase their diameter) that allow blood to flow more easily. Blood returning from the body in the veins must be pumped by the heart through the lungs and into the body's arteries against the high pressure in the arteries.
In order to accomplish this work, the heart's muscle must produce and use energy ("fuel"), and this requires consumption of oxygen that is. Because CRP levels can be temporarily increased by many situations such as a cold or going for a long run, the test should be done twice, two weeks apart.
An hs-CRP level above milligrams per liter (mg/L) indicates a higher risk of heart disease. Combining your hs-CRP test and other blood test results with your heart disease risk factors gives your doctor a picture of your overall heart. In all subgroups examined, including those with or without chest pain, troponin elevation, chronic nitrate use, and known prior history of coronary disease, there was again no demonstrable benefit or harm when nitrates were used acutely in the ED setting.
Since the first demonstration of a blood pressure lowering effect of sodium nitrate, many studies addressing the cardiovascular effects of inorganic nitrate and nitrite therapy on patients' endothelial dysfunction, high blood pressure, heart failure and coronary artery disease have been published, in part with mixed results (Table 1, Table 2).
Nicorandil and long-acting nitrates are effective drugs for the treatment of chronic stable angina in patients with effort-induced symptoms arising from epicardial coronary artery stenoses, as well as coronary vasospasm and microvascular angina. some nitrates include: *dilatrate-sr, iso-bid, isonate, isorbid, isordil, isotrate, sorbitrate (isosorbide dinitrate) *imdur (isosorbide mononitrate) *bidil (hydralazine with isosorbide dinitrate.
Coronary artery disease (CAD) is the most common form of heart disease. It is the result of atheromatous changes in the vessels supplying the heart. CAD is used to describe a range of clinical disorders from asymptomatic atherosclerosis and stable angina to acute coronary syndrome (unstable angina, NSTEMI, STEMI).
In the US, it is still one of the leading causes of mortality. 2 Furthermore, a review of 52 patients from the Global Registry of Acute Coronary Evidence shows that longer-term use of nitrates is associated with fewer ST elevation myocardial infarctions but more non-ST elevation acute coronary syndromes.
3 One hypothesis is that nitrates might pre-condition the heart more towards ischaemic episodes. Journals & Books; Help Download full Heart Journal.
VolumeIssue 1, Part 2, JulyPages Newer technologies for study of the action of nitrates in coronary circulation and myocardial function. Author links Studies in patients with and without coronary heart disease have identified apparent improvement in regional and.
Rose G, Hamilton PS, Keen H, Reid DD, McCartney P, Jarrett RJ. Myocardial ischaemia, risk factors and death from coronary heart-disease. Lancet. Jan 15; 1 ()– Shaper AG, Cook DG, Walker M, Macfarlane PW.
Prevalence of ischaemic heart disease in middle aged British men. Br Heart J. Jun; 51 (6)– Hemodynamic Interaction of Beta-Blockers and Nitrates in Coronary Heart Disease.- Discussion.- IV Coronary Flow, Perfusion.- Effect of Nitrates on Myocardial Blood Flow During Angina: Comparison of Results Obtained by Inert Gas Clearance and Thallium Imaging.- Collateral Pressure Distal to Coronary Obstructions - Influence of Nitrates Coronary heart disease (CHD) is one of the most common and serious diseases in the United States, affecting 12 million Americans.
This new edition addresses the concerns of those diagnosed with CHD, giving the most up-to-date and concise information regarding the disease and its treatment s: 4. Nitrates promote vasodilation of coronary arteries and veins. Beta blockers and calcium channel blockers are also used to decrease workload of the heart and decrease oxygen demands.
Nitrates may come in a variety of routes, such as sublingual, extended-release tablets, creams, transdermal patches, and intravenously.Transdermal nitrates in ischaemic heart disease. [R W Elsdon-Dew; G F B Birdwood; Geigy Pharmaceuticals.;] Print book: Conference publication: EnglishView all editions and formats: Rating: # Coronary heart disease--Chemotherapy\/span>\n \u00A0\u00A0\u00A0\n schema.The organic nitrates are a safe and effective choice for the management of ischemic syndromes related to coronary heart disease.
Although the anti-ischemic effects of these compounds have been recognized for more than a century, the mechanisms by which they exert their beneficial effects are still being delineated.